When the NCAA men’s basketball tournament resumed with regional semifinal action Thursday night, one team asserted itself as the new team to beat, while another entered the favorite conversation by knocking off one of the remaining contenders.

Arizona returned to favorite status at +240 to win the national championship after its manhandling of Arkansas, a spot the Wildcats held (at longer odds) coming out of the first weekend. At BetMGM, Arizona has the largest percentage of tickets and handle, which includes a $50,000 wager at +450 odds, but is not considered a liability with the sportsbook.

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Meanwhile, Illinois moved to its shortest title odds of the tournament at +750, fourth on the odds board, when it eliminated Houston, which had been at +700 going into Thursday’s action. Purdue also got a slight bump following its win (13-1 to 12-1), while this year’s Cinderella story, Iowa, made a huge move up from 120-1 to 45-1.

One-seeds Michigan (+350) and Duke (+370) will look to overtake Arizona when they get back in action Friday.

Odds by DraftKings Sportsbook, subject to change.

2026 Men’s College Basketball Championship(Seed) SchoolRecordTo WinFinalsSemisNext Game(1) Arizona Wildcats

32-2
+240
-105
-270
(1) Michigan Wolverines
31-2
+350
+175
-150
-485
(1) Duke Blue Devils
32-2
+370
+160
-125
-285
(3) Illinois Fighting Illini
24-8
+750
+240
-290
(2) Purdue Boilermakers
26-8
12-1
+450
+220
(2) Iowa State Cyclones
27-7
17-1
+550
+250
-185
(2) UConn Huskies
29-5
25-1
11-1
+450
-125
(3) Michigan State Spartans
25-7
30-1
12-1
+475
+105
(5) St. John’s Red Storm
28-6
35-1
13-1
+500
+230
(9) Iowa Hawkeyes
21-12
45-1
14-1
+235
(6) Tennessee Volunteers
22-11
60-1
18-1
+700
+154
(4) Alabama Crimson Tide
23-9
130-1
60-1
14-1
+370

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